|
KMID : 0385019900060010001
|
|
Korean Journal of Laboratory Animal Science
1990 Volume.6 No. 1 p.1 ~ p.5
|
|
|
Acute Toxicity Study of Bovine Somatotrophin in Rats and Mice
|
|
|
|
|
Abstract
|
|
|
This study was carried out to investigate whether acute toxicity of Bovine somatotrophin(BST) is or not.
Single dose of BST was given to both sexes of Sprague-Dawley rats and mice, subcutaneously. Any significant toxic symptom was not observed in treated rats and mice daring the experimental period.
Microscopic examination on the organs of tested animals showed no abnormal findings. In general toxicological aspects, BST was practically nontoxic in rats up to a single dose of 200 times and in mice 1000times of clinical dose equivalent via subcutaneous administration.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|